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The weight loss removes the fatty padding of the vulva, while the lack of estrogen thins the skin and reduces moisture, leading to changes in both appearance and comfort
The STEP 1 trial for semaglutide 2.4mg showed 14.9% average weight loss at 68 weeks
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These changes may weaken immune function, increase susceptibility to infections, and alter inflammatory responses (Cantoni et al., 2022
Benvenga S, Amato A, Calvani M, et al
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